Arun Chaudhury
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Publications

Inhibitory purinergic neuromuscular transmission

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Myosin Va and inta-varicosity transport of purinergic vesicles: critical role in enteric purinergic neurotransmission and genesis of fast IJP ( fast inhibitory junction potential)

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Myosin Va and intra-varicosity transport of nNOS: critical role in enteric nitrergic neurotransmission and genesis of slow IJP (slow inhibitory junction potential)

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Diverse pathophysiological spectrum of achalasia

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Evidence against role of ICC during enteric neuromuscular neurotransmission

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Normal Esophageal Motility

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PSD95 and membrane-bound nNOS

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PIN/LC8 is associated with cytosolic but not membrane-bound nNOS in thenitrergic varicosities of mice gut: implications for nitrergic neurotransmission

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LC8 and intra-varicosity transport of nNOS

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Active and inactive pools of nNOS

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Cisplatin and Visceral Sickness

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Changes in nitrergic innervation

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  • About


    Arun Chaudhury’s discoveries of the role of myosin motor proteins as the molecular basis of tandem release of neurotransmitters have provided the basis for our understanding of neuronal co-transmission. These findings provide basis for understanding of molecular pathophysiology of defective neurotransmitter release, which provide insights into irritable bowel syndrome and idiopathic gastroparesis and other gastrointestinal motility disorders which were hitherto labeled as “functional” disorders due to lack of comprehension of the molecular medicine. Loss of myosins, resulting in lack of nNOS recruitment to active zone of nitrergic nerve terminals, may also explain multiorgan complications of long-standing diabetes mellitus that manifest as gastroparesis and erectile dysfunction.

  • Recent Posts
    • Chirayita Restores Insulin and Myosin Va in Diabetic Rat Pancreas
    • Macromolecular assembly of nitrergic neurotransmission in gastric smooth muscle nerve terminals
    • A Case of Foreign Body Ingestion: Tongue Ring
    • Lessons in Neurogastroenterology from rare disorders
    • Morbidity & Mortality
    • Characterization of a novel amastin-like surface protein (ALSP) of Leishmania donovani, a probable lipase
    • Functional Bowel Disorders: Some Lessons from Sexual Medicine
    • HSV and Enteric Myopathy
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    • Publications
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      • Unpublished
      • Book Chapters
    • Presentations
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